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In this process, DHODH functions concurrently with the mitochondrial GPX4, separate from the cytoplasmic GPX4 and FSP1 (55)

6c,d) demonstrating that the peptide stability improvement, conferred by the disulphide bridge, is translatable across species and independent of the different protease environments

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Current mechanistic understandings of lymphedema and lipedema: tales of fluid, fat, and fibrosis

Cancer Research Applications Glutathione presents a complex dual role in cancer research: Tumor Cell GSH Levels: Investigation of elevated GSH in cancer cells and implications for cell proliferation Chemotherapy Resistance: Studies on GSH-mediated drug resistance mechanisms in tumor cells GSH Depletion Strategies: Research on buthionine sulfoximine (BSO) and other GSH-depleting agents to sensitize tumors Radiation Sensitivity: Examination of GSH status and radiation-induced oxidative damage in tumor vs