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The starting dose affected side effects but not final outcomes

However, further research is still needed to confirm whether retatrutide is safe for long-term use

More than 95% of prediabetic subjects on tirzepatide achieved normoglycemia at the end of the trial

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The conflicting safety signal One real-world evidence study found that patients receiving GLP-1 receptor agonists had higher risks of certain autoimmune conditions, including ulcerative colitis, rheumatoid arthritis, autoimmune thyroiditis, ankylosing spondylitis, and psoriasis, compared to those on DPP-4 inhibitors