Its clinical manifestations include itchy, erythematous papules and patches, and sometimes vesicles arranged in a reticular pattern (234, 235)
Advances in Experimental Medicine and Biology, vol 1480
For therapeutics this means: native human amylin cannot be administered as a drug, it aggregates already in the syringe and in the subcutis
Pharmacological characterization of mono-, dual- and tri-peptidic agonists at GIP and GLP-1 receptors
Nat Rev Immunol 11:98107 Mittal R, Malhotra S, Pandhi P, Kaur I, Dogra S (2009) Efficacy and safety of combination acitretin and pioglitazone therapy in patients with moderate to severe chronic plaque-type psoriasis: a randomized, double-blind, placebo-controlled clinical trial
Early studies suggest links to improved glucose metabolism and better control of cravings