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The receptor expression is lost in the corticotroph adenomas of patients with Cushings disease, which could be the potential mechanism of resistance to feedback of the HPA axis seen in these patients (212)

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Glutathione deficiency is associated with an increased risk of chronic disease, including Cancer Diabetes Heart disease Liver disease Autoimmune disease Low glutathione is also associated with aging

Lebers disease B12 injections could cause permanent optic nerve damage and even blindness in someone with this inherited eye disorder

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