At the class level, both have a GI-dominant profile (nausea, vomiting, diarrhoea) that concentrates at dose escalation
Common manifestations include ovarian cysts, irregular menstrual periods, impaired fertility, obesity, hirsutism, acne and increased risk of cardiovascular disease
The weight-loss data is impressive, but the other reason Im paying attention is what this drug tells us about where metabolic health is moving
You should be self-motivated enough to manage your own diet and exercise without structured coaching
(See below!) Consensus report on safe use of GLP-1 medications in T1D Despite the fact that GLP-1 receptor agonists (and dual GLP-1/GIP receptor agonists) are not FDA-approved for use in T1D for any indication, people with T1D are still able to access these drugs since they are approved to treat obesity and overweight
Researchers care about it because it acts on three hormone pathways at once: GLP-1, GIP, and glucagon