In addition to directly influencing satiety and appetite control via hypothalamic and hindbrain pathways, GLP-1RAs appear to engage higher-order networks involved in reward processing and emotional regulation, such as the insula, amygdala, and medial prefrontal cortex
And they can achieve a slow, gradual weight loss, usually over the course of two years, potentially more, and then be seen for weight maintenance
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Use your genes to find your susceptibility: GLP-1s make it easy not to eat, which can end up causing nutritional deficiencies if you arent eating enough nutrient-dense whole foods
The trial involved 338 adults, with close to a 50/50 split of men and women
