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Theres some evidence that daily tadalafil may have a small effect in lowering blood pressure, which could benefit men with untreated hypertension.12 But if you dont have high blood pressure, or youre already on medication for it, adding a PDE5 inhibitor to the mix can result in a pressure drop that could be dangerous.5 Hence, they are prescription-only, and healthcare providers are responsible for determining suitability

For some patients with significant volume loss, full correction may be best achieved by performing the treatment over sequential sessions to minimize the risk of overcorrection and reduce the potential for adverse events and complications

However, these benefits are mediated via vastly different mechanisms

10.1016/j.cub.2011.09.040 Curr

If you experience discomfort, scale back use and consult a doctor if symptoms persist