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In severe cases, decreased BMI Z scores, vitamin E deficiency, and an increased risk of abnormal glucose metabolism at 12 months have been observed

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However, this outcome is not inevitable

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221 The addition of L-citrulline (a precursor of the L-arginine cycle and NO synthesis) to medications in obese asthmatic patients may assist in asthma control and improve fractional NO excretion (FeNO) levels