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A lysine-based thermal MR process (at 120 C for 30-min) converts rutin to less-polar quercetin with increased ROS-scavenging activity in hepatocytes 620

[DOI] [PubMed] [Google Scholar] 68.Sugimoto K., Yasujima M., Yagihashi S

Tschandl P, Berghoff AS, Preusser M, Pammer J, Pehamberger H, Kittler H

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This timeline is speculative and subject to change based on regulatory processes

Current Canadian pricing for established GLP-1 medications remains substantial: Mounjaro: Approximately $300-400 monthly depending on dose Zepbound: Similar pricing structure to Mounjaro Ozempic: $200-300 monthly across different strengths Wegovy: $400-500 monthly for maintenance doses Regulatory Pathway in Canada For Pfizer's long-acting GLP-1 drug to reach Canadian patients, the company must complete clinical trials and submit a New Drug Submission to Health Canada