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Such a significant reduction in iron release could conceivably diminish both inflammation and oxidative stress, the latter being a condition where damaging oxidative processes occur more rapidly than the body's ability to counteract them, in the affected tissues

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There has been some support for the idea that Bcl-2 along with the 2-oxoglutarate carrier function as GSH transporters, based on correlations between Bcl-2 expression and nuclear GSH levels in cancer, however, this idea has been abandoned since the 2-oxoglutarate carrier has been refuted as a GSH transporter [76,78]