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In extreme instances, orthopedic diseases can even result in life-threatening complications

Overview of Berberine Berberine is a bioactive compound found in several plants, including Berberis vulgaris (barberry) and Coptis chinensis (Chinese goldthread)

On the other hand, semaglutide, a member of the GLP-1 receptor agonist class, functions through a different mechanism

Astrocytes become dysfunctional after TBI, and, specifically within the hyperacute period, they can significantly contribute towards secondary injury by propagating excitatory cytotoxicity, cellular edema, neuroinflammation, and dysregulated metabolism [72]

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