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FAK-Paxillin Cell Migration System Focal adhesion kinase and paxillin work together to drive cell migration toward injury sites

Umbilical Cord-Derived Mesenchymal Stromal Cells (MSCs) for Knee Osteoarthritis: Repeated MSC dosing is superior to a single msc dose and to hyaluronic acid in a controlled randomized Phase I/II trial

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For example, PINK1 and Parkin loss of function impair mitophagy and cause accumulation of damaged mitochondria, leading to enhanced electron leakage and formation of superoxides 11,12,13