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Combination therapy (PEG plus lactulose) was more effective than lactulose alone in improving HESA scores at 24 h and was associated with reduced length of hospital stay and with no significant differences in blood ammonia levels or serious adverse events

Abnormal bleeding, chronic cough, or hoarseness

What is medically supervised weight management

The most frequently reported adverse effects are gastrointestinal in nature and are related to the drug's mechanism of action, which slows gastric emptying and enhances satiety

A potential mechanism of PGC-1 induction is the activation of GPR109 (G-protein coupled receptor 109, also known as hydroxycarboxylic acid receptor 2, HCA2) by its ligand HB (9092)