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Liraglutide and Semaglutide are both GLP1R single-target agonists developed by Novo Nordisk

Semaglutide should be discontinued at least 2 months before a planned pregnancy due to its long half-life

There is also a pill called Contrave, which combines buproprion and naltrexone and is FDA-approved for weight management, with weight loss of up to 8% after a year

Considering whether other medical issues are affecting weight maintenance, such as sleep apnea, thyroid concerns, menopause, testosterone changes, medications, pain, or depression

Type 2 Diabetes: To help control blood sugar levels

GLP-1RAs can reduce the IL-6/STAT3 signaling pathway and enhance the cytotoxicity of NK and CD8 + T cells, potentially promoting the elimination of cancer cells (Lu et al., 2021