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In vivo studies have shown that microneedle-mediated delivery of semaglutide analogs leads to comparable or improved pharmacokinetics versus subcutaneous injections, with potential for once-weekly or biweekly dosing schedules [42]

Wegovy is FDA-approved specifically for chronic weight management at a higher dose (2.4 mg versus Ozempics 1 mg maximum)

This dual mechanism is one reason tirzepatide has shown strong results in clinical weight management research compared with GLP-1-only treatment

Additionally, HRT may offer benefits for bone health and reduce the risk of osteoporosis

Abbasinejad, MD , at Cape Fear Physical Medicine and Rehab, helps patients choose the right treatment based on their individual needs and health goals, offering personalized guidance on which medication might be more effective for weight loss