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These effects are believed to result from the drugs action on GLP-1 receptors in the gastrointestinal tract, leading to delayed gastric emptying and decreased appetite

De forma caracterstica, este efecto se atena al ir disminuyendo progresivamente los niveles de glucosa circulante, lo que condiciona una reduccin de los niveles de insulina y una restauracin de la secrecin del glucagn, con lo que se aleja la posibilidad de una hipoglucemia

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In addition, in colorectal cancer and glioblastoma, stable NAMPT-overexpressing cells were substantially more resistant to the apoptosis induced by diverse chemotherapeutic treatments than were their parental counterparts