glutathione affinity chromatography Separopore® 4B Also available in 96 Determination of glutathione and glutathione

Sometimes, however, it needs a little help

How it Affects You: Both smoking and air pollutants introduce high amounts of toxins, causing your body to deplete glutathione rapidly to defend itself

Despite its advantages, GST is a dimeric enzyme, and its crystal structure reveals four exposed cysteine residues that can be easily oxidized to form aggregates 20

It is synthesised in the cytosol by glutamate-cysteine ligase (EC 6.3.2.2) and glutathione synthetase, with the first, rate-limiting step feedback-inhibited by glutathione itself and intracellular concentrations typically 1 to 8 mM (Griffith, Free Radical Biology and Medicine, 1999)

Rupa Health

Research-context information only