Similarly, both lixisenatide 163 and dulaglutide 160 administration led to positive changes in different paradigms of depression induced in mice
When metabolic stress occurs, MOTS-c in cells can be transferred to the nucleus in an AMPK-dependent manner and bind to transcription factors regulated by ARE, thus improving the stress resistance of cells (16, 24)
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Notably, shGDH1 cells also expressed lower levels of ACCs, the first rate-limiting de novo lipogenic enzymes (Fig
doi: 10.1007/s11912-018-0675-0