In PsO, clinical studies evaluating GLP-1RAs such as liraglutide and semaglutide have reported significant improvements in PASI scores and histopathological skin features, effects that appear to be at least partially independent of weight loss (50, 53, 54)
To lead to weight loss, these medications are prescribed in two to five times the dose needed to treat diabetes, Dr
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7 Wadden TA et al