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Data from CVOTs of oral semaglutide (PIONEER 6) and liraglutide (LEADER) were not captured in the present analysis, which could be seen as a limitation

Free radicals occur when cells use oxygen to produce energy

, Nadeem, Kumar, and Yeo et al

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It can arise from many influences, including genetics, hormonal shifts, stress, medications, and underlying health conditions

Hence, modestly diminished GLP-1 action in diabetic subjects does not likely contribute to the defective glucose-stimulated glucagon suppression that remains a characteristic of diabetic subjects 3