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These medications should be a jump start toward a healthy lifestyle with diet and exercise, not a substitute, says the lead author, John Gabriel Horneff III, MD, an associate professor of orthopedic surgery at the University of Pennsylvania in Philadelphia

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As a pro-inflammatory cytokine, IL-6 participates in the acute phase reaction and stimulates immune responses, especially during infection and tissue damage (102)

While caffeine doesnt directly cause sleep paralysis, it can cause insomnia which is associated with sleep paralysis

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Participants received once-daily subcutaneous semaglutide at doses of 0.1 mg (80 patients), 0.2 mg (78 patients), 0.4 mg (82 patients), or placebo (80 patients)