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Given that both APR-017 and LCS3 are involved in inhibiting the GSH synthesis metabolism pathway, we examined whether the lethal effects of APR-017 and LCS3 on VRK2-deficient cells were due to inhibition of GSH

Topiramate affords neuroprotection in diabetic neuropathy model via downregulating spinal GFAP/inflammatory burden and improving neurofilament production

A healthy balance of reduced and oxidized forms of L-glutathione supports the bodys ability to detoxify chemicals such as those found in environmental pollutants, smoke and exhaust, heavy metals, and metabolites from various types of drugs

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PMID: 1397775