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However, it has become important to confirm the clinical relevance and durability of the potential benefits in different population groups who are not necessarily required to lose weight through well-designed and adequately powered trials

Boehringer Ingelheim's Jascayd (nerandomilast) has received a positive CHMP opinion the first selective PDE4B inhibitor in pulmonary fibrosis

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You can read more about this here: A review of adverse effects from IV glutathione