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Figure 1 2 MASLDs pathophysiology and current treatment MASLD is characterized by an abnormal accumulation of lipids in hepatocytes, commonly occurring in the context of obesity, insulin resistance, and T2DM-key features of metabolic syndrome that substantially affect patient quality of life and long-term prognosis (1)

The activation of TGR5 triggers the production of intracellular cAMP and secondary active the mitogen activated protein kinase signaling pathway to perform different functions in various organs

J Photochem Photobiol, B 63:818

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Noticeable benefits like improved elasticity, reduced wrinkles, and smoother skin usually appear after 8-12 weeks, with maximum results around 16 weeks or more