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Alcohol decreases glutamate's ability to bind with NMDA and acts as an antagonist of the NMDA receptor, which plays a critical role in LTP by allowing Ca2+ to enter the cell
The gut-barrier connection here is central: intestinal permeability (leaky gut) and immune dysregulation arent separate problems
Adding it at that stage is a strategic choice rather than an arbitrary one
If vitamin B12 is found to be low in the blood that is considered to be the final stage of B12 deficiency
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