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doi: 10.1016/j.urology.2005.04.012

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There are two key mechanisms to understand: 1

If you are well hydrated and havent urinated recently, you may pass some fluids more quickly than if the reverse is true (keeping in mind most people are dehydrated and many do not even know it)

That absence is not a footnote, it is the single fact that determines what you can and cannot do with this compound in a laboratory