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We review evidence suggesting that, collectively, these unresolved exogenous and endogenous cues drive liver injury, culminating in liver fibrosis and advanced sequelae of this disorder such as liver cirrhosis and hepatocellular carcinoma

Those with mineral or vitamin deficiencies can also benefit from dietary supplements

Treatment requires specialist initiation, regular monitoring of weight and metabolic parameters, and should be discontinued if response criteria are not met or intolerable effects occur

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Serum iron levels peak sometime between 2 and 6 hours after ingestion

No caffeine or stimulants