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Expert Opin Med Diagn 2011

Wait, where are you in birth order with these eight folks

These issues include whether plaintiffs can prove general causation, and whether the lawsuits are preempted by federal law

According to the MHRA-approved SmPC, the most frequently reported side effects are gastrointestinal in nature and include: Nausea (very common, affecting more than 1 in 10 people) Diarrhoea (very common) Constipation (very common) Vomiting (very common) Abdominal pain (very common) Headache (very common) Fatigue (common, affecting up to 1 in 10 people) Dyspepsia (indigestion, common) These gastrointestinal effects typically occur during dose escalation and often improve as the body adjusts to the medication

None of these are dose recommendations

The Phase 2 trial specifically tested starting at 4mg versus 2mg and found that higher starting doses produced significantly more GI side effects without faster weight loss