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Protein purification was performed as same as above, following the previously reported method 36

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Second, oral Wegovy at the higher 25 mg dose has been approved in the US since December 2025

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Two antibodies were chosen for further analysis: FLAG M2, which has have been successfully used in other ChIP experiments [82,83], and anti-GFP antibody, which immunoprecipitated the highest amount of LAG-1 ( S4B Fig )

Nausea, vomiting, constipation, diarrhea, bloating, gas, gastritis, and fatigue typically most pronounced during initiation and dose escalation