People with a diagnosed deficiency, pernicious anaemia, certain digestive disorders, or a vegan diet may benefit
The reactions people describe most often are anxiety, heart palpitations, and headaches
The long-term benefits for athletes or individuals engaged in regular physical activity include improved performance and reduced muscle fatigue
These were in the cerebellum (ibuprofen [238], paracetamol [239]), the cerebral cortex (diclofenac [240,241], celecoxib [201]), the frontoparietal cortex (concussive brain trauma) [231], the hippocampus and the cerebral cortex (insulin) [242], and the parietal neocortex and the hippocampus (cuprizone [232])
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The average weight loss of 2-3 kg over 12 weeks, while statistically significant, is substantially less than results achieved with appetite-suppressing medications or intensive dietary interventions