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Outcomes vary by individual, dose, cycle length, and quality of source material

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2006 PMID: 16289566 Hadley ME, Dorr RT 2004 PMID: 15073503 Diamond LE, et al

The Phase 2 and Phase 3 trials so far have shown a safety profile broadly consistent with other GLP-1 medications: gastrointestinal side effects are common, and a new signal called dysaesthesia (an abnormal skin sensation) appears more often at higher doses

Efficacy and safety of once-weekly semaglutide versus once-daily insulin glargine as add-on to metformin (with or without sulfonylureas) in insulin-naive patients with type 2 diabetes (SUSTAIN 4): a randomised, open-label, parallelgroup, multicentre, multinational, phase 3a trial

Policymakers must work to enact legislation that promotes price transparency, encourages generic drug competition, and enables Medicare to negotiate drug prices