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Is it ok to combine two medications that are components of FDA-approved medications, if those FDA-approved medications were originally indicated for diabetes

To make it work, they had to use specialized coatings, absorption enhancers, and strict dosing instructions

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Second, the strength of tirzepatides evidence is exactly what makes an apples-to-apples ranking against an investigational amylin analog impossible: you cannot fairly rank a fully-approved drug against a candidate whose stand-alone efficacy stops at Phase 2

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Transient Permeation Enhancer (TPE) technology for oral delivery of octreotide: a technological evaluation