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Phase 3 data shows up to 71.2 pounds at 68 weeks

Aravindhan, K

GBD 2015 Obesity Collaborators, Afshin A, Forouzanfar MH, Reitsma MB, Sur P, Estep K, et al

Herein, we review the evolution of GLP-1 therapy from its discovery and the development of currently approved drugs to the unprecedented endeavor to administer GLP-1 receptor agonists via the oral route

Its extraordinarily difficult to bypass those mechanisms to allow enough drug to be absorbed in an efficient manner, he says