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It has acetylcholinesterase inhibition properties, which means it increases levels of acetylcholine within the body

In the cohort of the 122 malignant peripheral nerve sheath tumors, complete loss of H3K27 trimethylation was observed in 50% of low-grade, 55% of intermediate-grade, and 80% of high-grade tumors

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If muscle symptoms are severe or persistent despite these interventions, clinicians should consider laboratory evaluation including creatine kinase, comprehensive metabolic panel with separate magnesium and calcium testing, thyroid function tests, vitamin D levels, and vitamin B12 levels to exclude alternative diagnoses

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