The first four weeks at 0.25 mg produce the mildest side effects
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10.1002/pul2.12221 85 DrabM.VerkadeP.ElgerM.KasperM.LohnM.LauterbachB.et al (2001)
Our laboratory has focused on a concept called Reward Deficiency Syndrome (RDS), which involves genetic and epigenetic factors that impair the brains reward system, leading to a reduced function of dopamine, a chemical in the brain associated with pleasure
Thus, one emerging hypothesis is that that increasing copper can react with reductive GSH, which might result in the decreased FDX1 and increased lipid peroxidation, further promoting oxidative damage [173,174,175]