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Isotretinoin is a powerful oral medication used to treat severe acne that has not responded to other therapies
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10.1016/j.fct.2012.08.028 119 Gmay
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PAB rats at both time points showed significant pathology compared to Sham, including RV dilation and dysfunction, which were recorded as increased right ventricular end-diastolic area (RVEDA), and decreased right ventricular fractional area change (RVFAC) and tricuspid annular plane systolic excursion (TAPSE)
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