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More recently, the SELECT trial expanded the conversation even further: it studied semaglutide 2.4 mg in people with overweight/obesity and established cardiovascular disease, but without diabetes, and found a significant reduction in major cardiovascular events

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(DAT, NET, and SERT) 2) By utilizing these transporters for its own uptake, amphetamine directly competes with endogenous dopamine, norepinephrine, and serotonin, thereby inhibiting their clearance from the synaptic cleft (Martin & Le, 2023)

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Statistical measures, including risk ratios and confidence intervals, were used to assess the relative risks of GI complications associated with each medication