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GHRP-6 is the better choice when maximum acute GH release is needed, when appetite stimulation serves the research goal, or when studying ghrelin-mediated effects beyond isolated GH release

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Most of the available research and clinical experience focuses on short- to moderate-term use, and the treatment is primarily prescribed for adults experiencing symptoms related to growth hormone deficiency

Afterwards, excessive ROS would interfere with Ca 2+ homeostasis in cardiomyocytes, affecting multiple ion transporters responsible for myocardial electrical activity and bringing about diastolic and systolic dysfunction and arrhythmia