35 cGAS-STING The cGAS-STING pathway senses cytosolic DNA under certain conditions, such as DNA damage, mitochondrial dysfunction, or nuclear envelope disruption
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As another transcriptional target of p53, the specific function of Zmat3 remains unclear, but it has been shown to influence the sensitivity of cells to apoptotic stimuli
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Lumholtz B, Kampmann TJ, Siersbaek-Nielsen K, Hansen JM