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The SURPASS-CVOT trial showed approximately 12% weight loss with tirzepatide compared with 5% with dulaglutide, along with nearly double the HbA1c reduction

The highest dose, 12 mg, produced a mean weight reduction of about 24.2%

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Interestingly, FGF21, SREBP-1c, and FAS mRNA in the liver tissues of the model group of mice and protein expression was increased compared with the control group, while liver kinase B1 (LKB1) mRNA expression was reduced

The Right Way to Use GLP-1 Medications GLP-1s should be part of a bigger picture plan , not the entire plan: Whole, real foods Protein + muscle support Hormone optimization Education + sustainability Final Thought GLP-1 medications are powerful

What Do the Clinical Trials Show