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doi: 10.3389/fcdhc.2025.1638681 Received 31 May 2025 Accepted 04 July 2025 Published 17 September 2025 Volume 6 - 2025 Edited by Dimitrios Patoulias, Aristotle University of Thessaloniki, Greece Reviewed by Louisa K

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It is well documented that pharmacological inhibition of GCL activity 4 or knockdown of the catalytic GCL subunit 5 increases ROS abundance, which mediates cellular damage

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