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Growth-hormone secretagogues such as CJC-1295 and Ipamorelin raise GH and IGF-1 gradually through the pituitary, while steroids act directly on muscle tissue

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Nature 380:435439 Henry TD, Annex BH, McKendall GR, Azrin MA, Lopez JJ, Giordano FJ, Shah PK, Willerson JT, Benza RL, Berman DS et al (2003) The VIVA trial: vascular endothelial growth factor in ischemia for vascular angiogenesis