Among the benefits for which L-theanine has been shown effective, youll find improvements in:4 Stress Sleep Neurological health (including memory and attention) Longevity Blood flow Theres also ample evidence that L-theanine can offset the less pleasant effects of caffeine and even work synergistically with caffeine to improve focus.14 15 Lets take a quick look at each of these potential benefits and what research says about them: Stress and anxiety In a Japanese study looking at the effects of 200mg of L-theanine, participants in the treatment groups verbal fluency and letter fluency improved in the face of stress compared to placebo.8 And a larger review of studies using 200-400mg doses found reductions in self-reported stress as well as improvements in stressor tasks, reaction time, and brain wave activity.16 Sleep L-Theanines sleep benefits are tied to its stress-reduction potential
Patients who already have reflux, constipation, irritable bowel symptoms, gallbladder history, diabetes medications, kidney concerns, low blood pressure, limited appetite, or difficulty maintaining protein intake should be especially proactive
doi: 10.1146/annurev-immunol-081619-104850 11 PollakNDlleCZieglerM
Injectable forms are typically used in clinical settings when a more direct and controlled approach is desired, allowing closer monitoring by a physician
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