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NNMT participates in biochemical pathways linked to cellular methylation processes, metabolic behaviour and internal signalling systems

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Above all, this work reflects the dedication of investigators, site teams, and patientswhose trust, collaboration, and commitment made this study possible

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Different clinical symptoms reported in individual patients with 5-oxoprolinase deficiency are renal stone formation, enterocolitis, mental retardation, neonatal hypoglycemia, microcytic anemia and microcephaly [4045]