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43,44,45,46 Other notable conditions frequently excluded were a history of cancer within 5 years (52%), immunocompromised state (45%), and vascular disease of the lower extremity (42%)

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In aged rat models, oral 5-amino-1mq capsules significantly improved myocardial mitochondrial function, reduced cardiomyocyte apoptosis, decreased myocardial injury markers (such as CK-MB, cTnI), enhanced cardiac contractility, and alleviated aging-related myocardial fibrosis

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