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97 In a model of lipopolysaccharide (LPS)-induced inflammation, liraglutide inhibited the polarization of pro-inflammatory microglia and promoted the polarization of anti-inflammatory microglia, diminished inflammatory cytokine expression, and decreased NF-B pathway activation

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However, when it undergoes the process of acetylation, which involves adding an acetyl group to a molecule, it has a greatly improved ability to cross the blood-brain barrier

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