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Nat Genet (2012) 44(8):8368

doi: 10.1097/01.CCM.0000050284.35609.97 57 XingLDongWChenYDaiWXiaoXLiuZet al

Role of enterohepatic recirculation in drug disposition: cooperation and complications

It is noteworthy that a behavioral analysis of Glp1r +/+ , Glp1r +/ and Glp1r/ mouse phenotypes and hippocampal Glp1r gene transfer demonstrated that deficiency of this receptor results in decrements in the acquisition of associative contextual learning which can be improved by hippocampal Glp1r somatic cell gene transfer [45]

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The key is understanding how methylation works, identifying your personal triggers, and applying strategies consistently