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Finally, we presented our insights on clinical concerns such as appropriate trial endpoints, management of comorbidities, and future developments

NICE has not issued guidance as no marketing authorisation has been granted

The mechanism of action involves several key physiological effects

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If possible, also track waist circumference weekly, body composition monthly (through DEXA or bioimpedance), and blood markers quarterly (fasting glucose, HbA1c, lipid panel, liver enzymes)