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Metabolic dysfunction-associated steatohepatitis (MASH) is a more dangerous form of MASLD, characterized by histological findings of inflammation in the liver parenchyma, hepatocyte ballooning with increased hepatocyte necrosis, and an elevated risk of fibrosis progression [7]

Biochim Biophys Acta 1837(1):5162 Zhou R, Pantel AR, Li S et al (2017) [(18)F](2S,4R)4-Fluoroglutamine PET detects glutamine pool size changes in triple-negative breast cancer in response to glutaminase inhibition

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332,333 The expression of HIF-2 is unaffected by prolonged hypoxia, thus, there is a shift in the quanlitative nature of HIF away from subunit 1 and towards subunit 2