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Starting at the lowest effective dose: Starting low is the best way to reduce GI side effects, but this has to be balanced with keeping your appetite at bay Gradual dose titration , as guided by your healthcare provider, can reduce GI symptoms Stay consistent: Side effects often lessen over time as your body adjusts Speak to your clinician: Your clinician can provide strategies to manage discomfort and monitor your response to the new medication Wegovy can be used long-term under the guidance of your healthcare provider

PLoS Pathog 15:e1007581 Fortalezas S, Marques-da-Silva D, Gutierrez-Merino C (2018) Creatine protects against cytosolic calcium dysregulation, mitochondrial depolarization and increase of reactive oxygen species production in rotenone-induced cell death of cerebellar granule neurons

Wong VW, Ekstedt M, Wong GL, Hagstrm H

Reported injuries include gastroparesis (stomach paralysis), bowel obstructions, severe vomiting, and gallbladder disease

Effect of resveratrol on 3-Nitropropionic acid-induced biochemical and behavioural changes: possible neuroprotective mechanisms

Solution: Follow the dosage instructions provided by your healthcare provider carefully